The last hydrolysis that releases the active oxytocin nonapeptide is catalyzed
by peptidylglycine alpha-amidating monooxygenase (PAM).[22]
釋放活性催產素九肽的最後一次水解是由肽酰甘氨酸α-醯胺化單加氧酶(PAM)催化的。[22]
The activity of the PAM enzyme system is dependent upon vitamin C (ascorbate),
which is a necessary vitamin cofactor.
PAM酶系統的活性取決於維生素C(抗壞血酸),維生素C是必需的維生素輔助因子。
By chance, sodium ascorbate by itself was found to stimulate the production of
oxytocin from ovarian tissue over a range of concentrations in a dose-dependent manner.
偶然地,發現抗壞血酸鈉本身在一定濃度範圍內以劑量依賴的方式刺激卵巢組織產生催產素。